Abstract

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This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).


General information 

  • Status
     : Published
    Publication date
     : 2021-02
  • Edition
     : 2
    Number of pages
     : 16
  • Technical Committee
     : ISO/TC 126 Tobacco and tobacco products
  • ICS
     :
    65.160 Tobacco, tobacco products and related equipment

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